Symbol
Name
ID

Kmt2e
lysine (K)-specific methyltransferase 2E
MGI:1924825

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

abnormal granulocyte differentiation

abnormal neutrophil differentiation

small thymus

thymus hypoplasia

decreased thymocyte number

abnormal definitive hematopoiesis

decreased common myeloid progenitor cell number

abnormal lymphopoiesis

decreased pro-B cell number

decreased double-negative T cell number

decreased double-positive T cell number

abnormal bone marrow cell morphology/development

abnormal myeloblast morphology/development

decreased erythrocyte cell number

low mean erythrocyte cell number

decreased hematocrit

increased hemoglobin concentration distribution width

decreased hemoglobin content

increased neutrophil cell number

thrombocytopenia

decreased B cell number

decreased pre-B cell number

decreased NK cell number

decreased NK T cell number

decreased T cell number

decreased macrophage cell number

decreased leukocyte cell number

decreased hematopoietic stem cell number

increased hematopoietic stem cell number

abnormal hematopoietic stem cell morphology

small spleen

spleen hypoplasia

abnormal neutrophil physiology

Availability

Mouse Genotype

Kmt2e^tm1.1Hjf/Kmt2e^tm1.1Hjf

Kmt2e^tm1Apa/Kmt2e^tm1Apa

Kmt2e^tm1Nik/Kmt2e^tm1Nik

Kmt2e^tm1.1Hjf/Kmt2e⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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